References to AdaptDx in Research
A growing number of peer-reviewed publications used the AdaptDx to investigate age-related macular degeneration and diabetic retinopathy.
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Relating retinal morphology and function in aging and early to intermediate age-related macular degeneration subjects
Sevilla MB, McGwin G, Lad EM, et al. Relating retinal morphology and function in aging and early to intermediate age-related macular degeneration subjects. American Journal of Ophthalmology. 2016;(165):65–77.
Vision-targeted health related quality of life in older adults: patient-reported visibility problems in low luminance activities are more likely to decline than daytime activities
Owsley C, McGwin G. Vision-targeted health related quality of life in older adults: patient-reported visibility problems in low luminance activities are more likely to decline than daytime activities. BMC Ophthalmology. 2016;(16):92.
Visual function in older eyes in normal macular health: association with incident early age-related macular degeneration 3 years later
Owsley C, Clark ME, Huisingh CE, Curcio CA, McGwin G. Visual Function in Older Eyes in Normal Macular Health: Association with Incident Early Age-Related Macular Degeneration 3 Years Later. Investigative Ophthalmology & Visual Science. 2016;57(4):1782–1789.
Comparison of visual function in older eyes in the earliest stages of age-related macular degeneration to those in normal macular health
Owsley C, Huisingh C, Clark ME, Jackson GR, McGwin G. Comparison of Visual Function in Older Eyes in the Earliest Stages of Age-related Macular Degeneration to Those in Normal Macular Health. Current Eye Research. 2016;41(2):266–272.
Delayed rod-mediated dark adaptation is a functional biomarker for incident early age-related macular degeneration
Owsley C, McGwin G, Clark ME, Jackson GR, et al. Delayed Rod-Mediated Dark Adaptation Is a Functional Biomarker for Incident Early Age-Related Macular Degeneration. Ophthalmology. 2016;123(2):344–351.
Associations between abnormal rod-mediated dark adaptation and health and functioning in older adults with normal macular health
Owsley C, Huisingh C, Jackson, GR, et al. Associations between abnormal rod-mediated Dark Adaptation and health and functioning in older adults with normal macular health. Investigative Ophthalmology & Visual Science. 2014;55(8):4776–4789.
Association between visual function and subretinal drusenoid deposits in normal and early age-related macular degeneration eyes
Neely D, Zarubina AV, Clark ME, et al. Association between visual function and subretinal drusenoid deposits in normal and early age-related macular degeneration eyes. Retina. 2017;37(7):1329–1336.
Prevalence of undiagnosed age-related macular degeneration in primary eye care
Neely D, Bray KJ, Huisingh CE, Clark ME, McGwin G, Owsley C. Prevalence of Undiagnosed Age-Related Macular Degeneration in Primary Eye Care. JAMA Ophthalmology. 2017;135(6):570–575.
Longevinex® improves human atrophic aged-related macular degeneration (AMD) photoreceptor / retinal pigment epithelium mediated dark adaptation
Richer S, Ulanski-II L, Bhandari A, Popenko N. Longevinex ® Improves Human Atrophic Aged-related Macular Degeneration (AMD) Photoreceptor / Retinal Pigment Epithelium Mediated Dark Adaptation. British Journal of Medicine and Medical Research. 2017;21(10):1–19.
Effect of doxycycline vs. placebo on retinal function and diabetic retinopathy progression in mild to moderate nonproliferative diabetic retinopathy: a randomized proof-of-concept clinical trial
Scott IU, Jackson GR, Quillen DA, Klein R, Liao J, Gardner TW. Effect of doxycycline vs. placebo on retinal function and diabetic retinopathy progression in mild to moderate nonproliferative diabetic retinopathy: a randomized proof-of-concept clinical trial. JAMA Ophthalmology. 2014;132(9):1137–1142.
Effect of doxycycline vs placebo on retinal function and diabetic retinopathy progression in patients with severe nonproliferative or non–high-risk proliferative diabetic retinopathy: a randomized clinical trial
Scott IU, Jackson GR, Quillen DA, et al. Effect of Doxycycline vs Placebo on Retinal Function and Diabetic Retinopathy Progression in Patients With Severe Nonproliferative or Non–High-Risk Proliferative Diabetic Retinopathy: A Randomized Clinical Trial. JAMA Ophthalmology. 2014;132(5):535.
Natural history of rod-mediated dark adaptation over 2 years in intermediate age-related macular degeneration
Owsley C, Clark ME, McGwin G. Natural History of Rod-Mediated Dark Adaptation over 2 Years in Intermediate Age-Related Macular Degeneration. Translational Vision Science & Technology. 2017;6(3):15.
Glucose variability and inner retinal sensory neuropathy in persons with type 1 diabetes mellitus
Stem MS, Dunbar GE, Jackson GR, Farsiu S, Pop-Busui R, Gardner TW. Glucose variability and inner retinal sensory neuropathy in persons with type 1 diabetes mellitus. Eye. 2016;(30):825-832.
Association of low luminance questionnaire with objective functional measures in early and intermediate age-related macular degeneration
Thompson AC, Luhmann UFO, Stinnett SS, et al. Association of Low Luminance Questionnaire with Objective Functional Measures in Early and Intermediate Age-Related Macular Degeneration. Investigative Ophthalmology & Visual Science. 2018;59(1):289.
Additional considerations in the utility of dark adaptometry for the diagnosis of age-related macular degeneration
VanderBeek BL. Additional Considerations in the Utility of Dark Adaptometry for the Diagnosis of Age-Related Macular Degeneration. Investigative Ophthalmology & Visual Science. 2014;55(5):3148–3148.
Decreased visual function scores on a low luminance questionnaire is associated with impaired dark adaptation
Yazdanie M, Alvarez J, Agrón E, et al. Decreased Visual Function Scores on a Low Luminance Questionnaire Is Associated with Impaired Dark Adaptation. Ophthalmology. 2017;124(9):1332–1339.
Rod-mediated dark adaptation and macular pigment optical density in older adults with normal maculas
Zarubina AV, Huisingh CE, Clark ME, et al. Rod-Mediated Dark Adaptation and Macular Pigment Optical Density in Older Adults with Normal Maculas. Current Eye Research. 2018;43(7):913–920.
Reduced central retinal artery blood flow is related to impaired central visual function in retinitis pigmentosa patients
Kayser, S., Vargas, P., Mendelsohn, D., Han, J., Bi, H., Benavente, A., & Bittner, A. K. (2017). Reduced Central Retinal Artery Blood Flow Is Related to Impaired Central Visual Function in Retinitis Pigmentosa Patients. Current Eye Research, 42(11), 1503–1510.
Longitudinal study of dark adaptation as a functional outcome measure for age-related macular degeneration
Chen, K. G., Alvarez, J. A., Yazdanie, M., Papudesu, C., Wong, W. T., Wiley, H. E., … Cukras, C. A. (2018). Longitudinal Study of Dark Adaptation as a Functional Outcome Measure for Age-Related Macular Degeneration. Ophthalmology.
Visual function metrics in early and intermediate dry age-related macular degeneration for use as clinical trial endpoints
Cocce, K. J., Stinnett, S. S., Luhmann, U. F. O., Vajzovic, L., Horne, A., Schuman, S. G., … Lad, E. M. (2018). Visual function metrics in early and intermediate dry age-related macular degeneration for use as clinical trial endpoints. American Journal of Ophthalmology.
The ARMS2 A69S polymorphism is associated with delayed rod-mediated dark adaptation in eyes at risk for incident age-related macular degeneration
Mullins, R. F., McGwin, G., Searcey, K., Clark, M. E., Kennedy, E. L., Curcio, C. A., … Owsley, C. (2018). The ARMS2 A69S Polymorphism Is Associated with Delayed Rod-Mediated Dark Adaptation in Eyes at Risk for Incident Age-Related Macular Degeneration. Ophthalmology.
Author response: additional considerations in the utility of dark adaptometry for the diagnosis of age-related macular degeneration
Jackson GR, Scott IU, Kim IK, et al. Author Response: Additional Considerations in the Utility of Dark Adaptometry for the Diagnosis of Age-Related Macular Degeneration. Investigative Ophthalmology & Visual Science. 2014;55(5):3149.
Determining optimal test parameters for assessing dark adaptation in people with Intermediate age-related macular degeneration
Binns AM, Taylor DJ, Edwards LA, Crabb DP. Determining Optimal Test Parameters for Assessing Dark Adaptation™ in People With Intermediate Age-Related Macular Degeneration. Investigative Ophthalmology & Visual Science 2018; 59: 114-121.
Randomized controlled trial of electro-stimulation therapies to modulate retinal blood flow and visual function in retinitis pigmentosa
Bittner AK, Seger K, Salveson R, et al. Randomized controlled trial of electro-stimulation therapies to modulate retinal blood flow and visual function in retinitis pigmentosa. Acta Ophthalmologica. 2018;96(3):366–376.
Multimodal characterization of proliferative diabetic retinopathy reveals alterations in outer retinal function and structure
Boynton GE, Stem MS, Kwark L, Jackson GR, Farsiu S, Gardner TW. Multimodal Characterization of Proliferative Diabetic Retinopathy Reveals Alterations in Outer Retinal Function and Structure. Ophthalmology. 2015;122(5):957–967.
Association between retinal thickness measured by spectral-domain optical coherence tomography (OCT) and rod-mediated dark adaptation in non-exudative age-related maculopathy
Clark ME, McGwin G, Neely D, et al. Association between retinal thickness measured by spectral-domain optical coherence tomography (OCT) and rod-mediated Dark Adaptation in non-exudative age-related maculopathy. Br J Ophthalmol. 2011;(95):1427–32.
Impairments in dark adaptation are associated with age-related macular degeneration severity and reticular pseudodrusen
Flamendorf J, Agrón E, Wong WT, et al. Impairments in Dark Adaptation Are Associated with Age-Related Macular Degeneration Severity and Reticular Pseudodrusen. Ophthalmology. 2015;122(10):2053–2062.
Dark adaptation during transient hyperglycemia in type 2 diabetes
Holfort SK, Jackson GR, Larsen M. Dark Adaptation during transient hyperglycemia in type 2 diabetes. Exp Eye Res. 2010;(91):710–4.
Retinal function in relation to improved glycaemic control in type 1 diabetes
Holfort SK, Norgaard K, Jackson GR, et al. Retinal function in relation to improved glycaemic control in type 1 diabetes. Diabetologia. 2011;(54):1853–61.
Twelve-month natural history of dark adaptation in patients with AMD
Jackson GR, Clark ME, Scott IU, Walter LE, Quillen DA, Brigell MG. Twelve-month natural history of Dark Adaptation in patients with AMD. Optometry and Vision Science: Official Publication of the American Academy of Optometry. 2014;91(8):925–931.
A short-duration dark adaptation protocol for assessment of age-related maculopathy
Jackson GR, Edwards JG. A short-duration Dark Adaptation protocol for assessment of age-related maculopathy. Journal of Ocular Biology, Diseases, and Informatics. 2008;1(1):7–11.
The effects of diabetic retinopathy and pan-retinal photocoagulation on photoreceptor cell function as assessed by dark adaptometry
Bavinger JC, Dunbar GE, Stem MS, et al. The Effects of Diabetic Retinopathy and Pan-Retinal Photocoagulation on Photoreceptor Cell Function as Assessed by Dark Adaptometry. Investigative Ophthalmology & Visual Science. 2018;57(1):208–217.
Diagnostic sensitivity and specificity of dark adaptometry for detection of age-related macular degeneration
Jackson GR, Scott IU, Kim IK, Quillen DA, Iannaccone A, Edwards JG. Diagnostic Sensitivity and Specificity of Dark Adaptometry for detection of Age-Related Macular Degeneration. Investigative Ophthalmology & Visual Science. 2014;(55):1427–1431.
Inner retinal visual dysfunction is a sensitive marker of non-proliferative diabetic retinopathy
Jackson GR, Scott IU, Quillen DA, Walter LE, Gardner TW. Inner retinal visual dysfunction is a sensitive marker of non-proliferative diabetic retinopathy. Br J Ophthalmol. 2011;(96):699–703.
Baseline haemoglobin A1c influences retinal function after long-term insulin pump therapy
Klefte ON, Holfort SK, Larsen M. Baseline haemoglobin A1c influences retinal function after long-term insulin pump therapy. Graefe’s Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. 2016;254(3):467–473.
Retinal characteristics during 1 year of insulin pump therapy in type 1 diabetes: a prospective, controlled, observational study
Klefter ON, Hommel E, Munch IC, Nørgaard K, Madsbad S, Larsen M. Retinal characteristics during 1 year of insulin pump therapy in type 1 diabetes: a prospective, controlled, observational study. Acta Ophthalmologica. 2016;94(6):540–547.
Health conditions linked to age-related macular degeneration associated with dark adaptation
Laíns I, Miller JB, Mukai R, et al. Heath Conditions Linked to Age-Related Macular Degeneration Associated with Dark Adaptation. Retina. 2018;38(6):1145–1155.
Peripheral changes associated with delayed dark adaptation in age-related macular degeneration
Laíns I, Park DH, Mukai R, et al. Peripheral Changes Associated With Delayed Dark Adaptation in Age-Related Macular Degeneration. American Journal of Ophthalmology. 2018;(190):113–124.
Structural changes associated with delayed dark adaptation in age-related macular degeneration
Laíns I, Miller JB, Park DH, et al. Structural Changes Associated with Delayed Dark Adaptation in Age-Related Macular Degeneration. Ophthalmology. 2017;124(9):1340–1352.
Dark adaptation changes in highly myopic patients
Messerlin A, Greth A, Bourcier T et al. Dark Adaptation changes in highly myopic patients. European Journal of Ophthalmology. July 2018.
Dark adaptation in relation to choroidal thickness in healthy young subjects: a cross-sectional, observational study
Munch IC, Altuntas C, Li XQ, Jackson GR, Klefter ON, Larsen M. Dark Adaptation in relation to choroidal thickness in healthy young subjects: a cross-sectional, observational study. BMC Ophthalmology. 2016;(16):105.
Pivotal Studies
Diagnostic sensitivity and specificity of dark adaptometry for detection of age-related macular degeneration
Jackson GR, Scott IU, Kim IK, Quillen DA, Iannaccone A, Edwards JG. Diagnostic Sensitivity and Specificity of Dark Adaptometry for detection of Age-Related Macular Degeneration. Investigative Ophthalmology & Visual Science. 2014;(55):1427–1431.
Delayed rod-mediated dark adaptation is a functional biomarker for incident early age-related macular degeneration
Owsley C, McGwin G, Clark ME, Jackson GR, et al. Delayed Rod-Mediated Dark Adaptation Is a Functional Biomarker for Incident Early Age-Related Macular Degeneration. Ophthalmology. 2016;123(2):344–351.
AMD
Association between visual function and subretinal drusenoid deposits in normal and early age-related macular degeneration eyes
Neely D, Zarubina AV, Clark ME, et al. Association between visual function and subretinal drusenoid deposits in normal and early age-related macular degeneration eyes. Retina. 2017;37(7):1329–1336.
The ARMS2 A69S polymorphism is associated with delayed rod-mediated dark adaptation in eyes at risk for incident age-related macular degeneration
Mullins, R. F., McGwin, G., Searcey, K., Clark, M. E., Kennedy, E. L., Curcio, C. A., … Owsley, C. (2018). The ARMS2 A69S Polymorphism Is Associated with Delayed Rod-Mediated Dark Adaptation in Eyes at Risk for Incident Age-Related Macular Degeneration. Ophthalmology.
Visual function metrics in early and intermediate dry age-related macular degeneration for use as clinical trial endpoints
Cocce, K. J., Stinnett, S. S., Luhmann, U. F. O., Vajzovic, L., Horne, A., Schuman, S. G., … Lad, E. M. (2018). Visual function metrics in early and intermediate dry age-related macular degeneration for use as clinical trial endpoints. American Journal of Ophthalmology.
Decreased visual function scores on a low luminance questionnaire is associated with impaired dark adaptation
Yazdanie M, Alvarez J, Agrón E, et al. Decreased Visual Function Scores on a Low Luminance Questionnaire Is Associated with Impaired Dark Adaptation. Ophthalmology. 2017;124(9):1332–1339.
Additional considerations in the utility of dark adaptometry for the diagnosis of age-related macular degeneration
VanderBeek BL. Additional Considerations in the Utility of Dark Adaptometry for the Diagnosis of Age-Related Macular Degeneration. Investigative Ophthalmology & Visual Science. 2014;55(5):3148–3148.
Association of low luminance questionnaire with objective functional measures in early and intermediate age-related macular degeneration
Thompson AC, Luhmann UFO, Stinnett SS, et al. Association of Low Luminance Questionnaire with Objective Functional Measures in Early and Intermediate Age-Related Macular Degeneration. Investigative Ophthalmology & Visual Science. 2018;59(1):289.
Relating retinal morphology and function in aging and early to intermediate age-related macular degeneration subjects
Sevilla MB, McGwin G, Lad EM, et al. Relating retinal morphology and function in aging and early to intermediate age-related macular degeneration subjects. American Journal of Ophthalmology. 2016;(165):65–77.
Longevinex® improves human atrophic aged-related macular degeneration (AMD) photoreceptor / retinal pigment epithelium mediated dark adaptation
Richer S, Ulanski-II L, Bhandari A, Popenko N. Longevinex ® Improves Human Atrophic Aged-related Macular Degeneration (AMD) Photoreceptor / Retinal Pigment Epithelium Mediated Dark Adaptation. British Journal of Medicine and Medical Research. 2017;21(10):1–19.
Prevalence of undiagnosed age-related macular degeneration in primary eye care
Neely D, Bray KJ, Huisingh CE, Clark ME, McGwin G, Owsley C. Prevalence of Undiagnosed Age-Related Macular Degeneration in Primary Eye Care. JAMA Ophthalmology. 2017;135(6):570–575.
Determining optimal test parameters for assessing dark adaptation in people with Intermediate age-related macular degeneration
Binns AM, Taylor DJ, Edwards LA, Crabb DP. Determining Optimal Test Parameters for Assessing Dark Adaptation™ in People With Intermediate Age-Related Macular Degeneration. Investigative Ophthalmology & Visual Science 2018; 59: 114-121.
Associations between abnormal rod-mediated dark adaptation and health and functioning in older adults with normal macular health
Owsley C, Huisingh C, Jackson, GR, et al. Associations between abnormal rod-mediated Dark Adaptation and health and functioning in older adults with normal macular health. Investigative Ophthalmology & Visual Science. 2014;55(8):4776–4789.
Comparison of visual function in older eyes in the earliest stages of age-related macular degeneration to those in normal macular health
Owsley C, Huisingh C, Clark ME, Jackson GR, McGwin G. Comparison of Visual Function in Older Eyes in the Earliest Stages of Age-related Macular Degeneration to Those in Normal Macular Health. Current Eye Research. 2016;41(2):266–272.
Visual function in older eyes in normal macular health: association with incident early age-related macular degeneration 3 years later
Owsley C, Clark ME, Huisingh CE, Curcio CA, McGwin G. Visual Function in Older Eyes in Normal Macular Health: Association with Incident Early Age-Related Macular Degeneration 3 Years Later. Investigative Ophthalmology & Visual Science. 2016;57(4):1782–1789.
Vision-targeted health related quality of life in older adults: patient-reported visibility problems in low luminance activities are more likely to decline than daytime activities
Owsley C, McGwin G. Vision-targeted health related quality of life in older adults: patient-reported visibility problems in low luminance activities are more likely to decline than daytime activities. BMC Ophthalmology. 2016;(16):92.
Author response: additional considerations in the utility of dark adaptometry for the diagnosis of age-related macular degeneration
Jackson GR, Scott IU, Kim IK, et al. Author Response: Additional Considerations in the Utility of Dark Adaptometry for the Diagnosis of Age-Related Macular Degeneration. Investigative Ophthalmology & Visual Science. 2014;55(5):3149.
A short-duration dark adaptation protocol for assessment of age-related maculopathy
Jackson GR, Edwards JG. A short-duration Dark Adaptation protocol for assessment of age-related maculopathy. Journal of Ocular Biology, Diseases, and Informatics. 2008;1(1):7–11.
Impairments in dark adaptation are associated with age-related macular degeneration severity and reticular pseudodrusen
Flamendorf J, Agrón E, Wong WT, et al. Impairments in Dark Adaptation Are Associated with Age-Related Macular Degeneration Severity and Reticular Pseudodrusen. Ophthalmology. 2015;122(10):2053–2062.
Association between retinal thickness measured by spectral-domain optical coherence tomography (OCT) and rod-mediated dark adaptation in non-exudative age-related maculopathy
Clark ME, McGwin G, Neely D, et al. Association between retinal thickness measured by spectral-domain optical coherence tomography (OCT) and rod-mediated Dark Adaptation in non-exudative age-related maculopathy. Br J Ophthalmol. 2011;(95):1427–32.
Natural History
Twelve-month natural history of dark adaptation in patients with AMD
Jackson GR, Clark ME, Scott IU, Walter LE, Quillen DA, Brigell MG. Twelve-month natural history of Dark Adaptation in patients with AMD. Optometry and Vision Science: Official Publication of the American Academy of Optometry. 2014;91(8):925–931.
Natural history of rod-mediated dark adaptation over 2 years in intermediate age-related macular degeneration
Owsley C, Clark ME, McGwin G. Natural History of Rod-Mediated Dark Adaptation over 2 Years in Intermediate Age-Related Macular Degeneration. Translational Vision Science & Technology. 2017;6(3):15.
Longitudinal study of dark adaptation as a functional outcome measure for age-related macular degeneration
Chen, K. G., Alvarez, J. A., Yazdanie, M., Papudesu, C., Wong, W. T., Wiley, H. E., … Cukras, C. A. (2018). Longitudinal Study of Dark Adaptation as a Functional Outcome Measure for Age-Related Macular Degeneration. Ophthalmology.
RP & Other
Randomized controlled trial of electro-stimulation therapies to modulate retinal blood flow and visual function in retinitis pigmentosa
Bittner AK, Seger K, Salveson R, et al. Randomized controlled trial of electro-stimulation therapies to modulate retinal blood flow and visual function in retinitis pigmentosa. Acta Ophthalmologica. 2018;96(3):366–376.
Health conditions linked to age-related macular degeneration associated with dark adaptation
Laíns I, Miller JB, Mukai R, et al. Heath Conditions Linked to Age-Related Macular Degeneration Associated with Dark Adaptation. Retina. 2018;38(6):1145–1155.
Peripheral changes associated with delayed dark adaptation in age-related macular degeneration
Laíns I, Park DH, Mukai R, et al. Peripheral Changes Associated With Delayed Dark Adaptation in Age-Related Macular Degeneration. American Journal of Ophthalmology. 2018;(190):113–124.
Structural changes associated with delayed dark adaptation in age-related macular degeneration
Laíns I, Miller JB, Park DH, et al. Structural Changes Associated with Delayed Dark Adaptation in Age-Related Macular Degeneration. Ophthalmology. 2017;124(9):1340–1352.
Dark adaptation changes in highly myopic patients
Messerlin A, Greth A, Bourcier T et al. Dark Adaptation changes in highly myopic patients. European Journal of Ophthalmology. July 2018.
Dark adaptation in relation to choroidal thickness in healthy young subjects: a cross-sectional, observational study
Munch IC, Altuntas C, Li XQ, Jackson GR, Klefter ON, Larsen M. Dark Adaptation in relation to choroidal thickness in healthy young subjects: a cross-sectional, observational study. BMC Ophthalmology. 2016;(16):105.
Rod-mediated dark adaptation and macular pigment optical density in older adults with normal maculas
Zarubina AV, Huisingh CE, Clark ME, et al. Rod-Mediated Dark Adaptation and Macular Pigment Optical Density in Older Adults with Normal Maculas. Current Eye Research. 2018;43(7):913–920.
Reduced central retinal artery blood flow is related to impaired central visual function in retinitis pigmentosa patients
Kayser, S., Vargas, P., Mendelsohn, D., Han, J., Bi, H., Benavente, A., & Bittner, A. K. (2017). Reduced Central Retinal Artery Blood Flow Is Related to Impaired Central Visual Function in Retinitis Pigmentosa Patients. Current Eye Research, 42(11), 1503–1510.
Diabetes
The effects of diabetic retinopathy and pan-retinal photocoagulation on photoreceptor cell function as assessed by dark adaptometry
Bavinger JC, Dunbar GE, Stem MS, et al. The Effects of Diabetic Retinopathy and Pan-Retinal Photocoagulation on Photoreceptor Cell Function as Assessed by Dark Adaptometry. Investigative Ophthalmology & Visual Science. 2018;57(1):208–217.
Multimodal characterization of proliferative diabetic retinopathy reveals alterations in outer retinal function and structure
Boynton GE, Stem MS, Kwark L, Jackson GR, Farsiu S, Gardner TW. Multimodal Characterization of Proliferative Diabetic Retinopathy Reveals Alterations in Outer Retinal Function and Structure. Ophthalmology. 2015;122(5):957–967.
Dark adaptation during transient hyperglycemia in type 2 diabetes
Holfort SK, Jackson GR, Larsen M. Dark Adaptation during transient hyperglycemia in type 2 diabetes. Exp Eye Res. 2010;(91):710–4.
Retinal function in relation to improved glycaemic control in type 1 diabetes
Holfort SK, Norgaard K, Jackson GR, et al. Retinal function in relation to improved glycaemic control in type 1 diabetes. Diabetologia. 2011;(54):1853–61.
Inner retinal visual dysfunction is a sensitive marker of non-proliferative diabetic retinopathy
Jackson GR, Scott IU, Quillen DA, Walter LE, Gardner TW. Inner retinal visual dysfunction is a sensitive marker of non-proliferative diabetic retinopathy. Br J Ophthalmol. 2011;(96):699–703.
Baseline haemoglobin A1c influences retinal function after long-term insulin pump therapy
Klefte ON, Holfort SK, Larsen M. Baseline haemoglobin A1c influences retinal function after long-term insulin pump therapy. Graefe’s Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. 2016;254(3):467–473.
Retinal characteristics during 1 year of insulin pump therapy in type 1 diabetes: a prospective, controlled, observational study
Klefter ON, Hommel E, Munch IC, Nørgaard K, Madsbad S, Larsen M. Retinal characteristics during 1 year of insulin pump therapy in type 1 diabetes: a prospective, controlled, observational study. Acta Ophthalmologica. 2016;94(6):540–547.
Effect of doxycycline vs. placebo on retinal function and diabetic retinopathy progression in mild to moderate nonproliferative diabetic retinopathy: a randomized proof-of-concept clinical trial
Scott IU, Jackson GR, Quillen DA, Klein R, Liao J, Gardner TW. Effect of doxycycline vs. placebo on retinal function and diabetic retinopathy progression in mild to moderate nonproliferative diabetic retinopathy: a randomized proof-of-concept clinical trial. JAMA Ophthalmology. 2014;132(9):1137–1142.
Effect of doxycycline vs placebo on retinal function and diabetic retinopathy progression in patients with severe nonproliferative or non–high-risk proliferative diabetic retinopathy: a randomized clinical trial
Scott IU, Jackson GR, Quillen DA, et al. Effect of Doxycycline vs Placebo on Retinal Function and Diabetic Retinopathy Progression in Patients With Severe Nonproliferative or Non–High-Risk Proliferative Diabetic Retinopathy: A Randomized Clinical Trial. JAMA Ophthalmology. 2014;132(5):535.
Glucose variability and inner retinal sensory neuropathy in persons with type 1 diabetes mellitus
Stem MS, Dunbar GE, Jackson GR, Farsiu S, Pop-Busui R, Gardner TW. Glucose variability and inner retinal sensory neuropathy in persons with type 1 diabetes mellitus. Eye. 2016;(30):825-832.